neighborhood deprivation

Does neighbourhood deprivation influence low back pain and arthritis: An empirical study using multilevel twin design

Objective: Neighbourhood deprivation has been found to be associated with many health conditions, but its association with low back pain (LBP) and arthritis is unclear. This study aimed to examine the association between neighbourhood deprivation with LBP and arthritis, and its potential interaction with individual socioeconomic status (SES) on these outcomes. Methods: Monozygotic (MZ) twins from the […]

Measuring and modelling perceptions of the built environment for epidemiological research using crowd-sourcing and image-based deep learning models

Background: Perceptions of the built environment, such as nature quality, beauty, relaxation, and safety, may be key factors linking the built environment to human health. However, few studies have examined these types of perceptions due to the difficulty in quantifying them objectively in large populations. Objective: To measure and predict perceptions of the built environment […]

Neighborhood Deprivation Moderates Shared and Unique Environmental Influences on Hazardous Drinking: Findings from a Cross-Sectional Co-Twin Study

Background: There has been increased interest in the interplay of genetic and environmental factors in the development of problematic alcohol use, including socioeconomic conditions of the neighborhood. Using a co-twin design, we examined the extent to which contributions of genetic, shared environmental, and unique environmental influences on hazardous drinking differed according to levels of neighborhood […]

Associations between neighbourhood characteristics and depression: a twin study

Background: Depression is an important contributor to the global burden of disease. Besides several known individual-level factors that contribute to depression, there is a growing recognition that neighbourhood environment can also profoundly affect mental health. This study assessed associations between three neighbourhood constructs-socioeconomic deprivation, residential instability and income inequality-and depression among adult twin pairs. The twin […]

Examination of Cross-Sectional Associations of Neighborhood Deprivation and Alcohol Outlet Density With Hazardous Drinking Using a Twin Design

Objective: The purpose of this study was to examine whether neighborhood socioeconomic deprivation and alcohol outlet density are associated with hazardous drinking using a co-twin design to control for confounding because of genetic and shared environmental factors. Method: The study sample included cross-sectional data from 1,996 same-sex adult twin pairs (mean age = 36.6; 65.9% female) from […]

Neighborhood deprivation and depression in adult twins: genetics and gene×environment interaction

Background: Depression is a significant problem and it is vital to understand its underlying causes and related policy implications. Neighborhood characteristics are implicated in depression but the nature of this association is unclear. Unobserved or unmeasured factors may confound the relationship. This study addresses confounding in a twin study investigating neighborhood-level effects on depression controlling for […]

Socioeconomic modifiers of genetic and environmental influences on body mass index in adult twins

Objective: Individual measures of socioeconomic status (SES) suppress genetic variance in body mass index (BMI). Our objective was to examine the influence of both individual-level (i.e., educational attainment, household income) and macrolevel (i.e., neighborhood socioeconomic advantage) SES indicators on genetic contributions to BMI. Method: The study used education level data from 4,162 monozygotic (MZ) and 1,900 dizygotic […]

Sleep Duration and Area-Level Deprivation in Twins

Study objectives: We used quantitative genetic models to assess whether area-level deprivation as indicated by the Singh Index predicts shorter sleep duration and modifies its underlying genetic and environmental contributions. Methods: Participants were 4,218 adult twin pairs (2,377 monozygotic and 1,841 dizygotic) from the University of Washington Twin Registry. Participants self-reported habitual sleep duration. The Singh Index […]

Genetic and environmental influences on residential location in the US

We used a classical twin design and measures of neighborhood walkability and social deprivation, using each twin’s street address, to examine genetic and environmental influences on the residential location of 1389 same-sex pairs from a US community-based twin registry. Within-pair correlations and structural equation models estimated these influences on walkability among younger (ages 18-24.9) and […]