Schur E, Carnell S. Purpose of Review Functional magnetic resonance imaging (fMRI) using visual food cues provides insight into brain regulation of appetite in humans. This review sought evidence for genetic determinants of these responses. Recent Findings Echoing behavioral studies of food cue responsiveness, twin study approaches detect significant inherited influences on brain response to […]
Silventoinen K, Jelenkovic A, Hopper JL, Busjahn A, Cozen W, Mack TM, Sumathipala A, Harris JR, Goldberg JH, Harden KP, Duncan GE, Buchwald D, Turkheimer E, Kaprio J, et al. Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences […]
Eney AE, Tsang S, Delaney JA, Turkheimer E, Duncan GE. Background Consumption of sugar-sweetened beverages, such as soda, have been shown to play an important role in weight gain. Although soda consumption has been associated with body mass index (BMI) in many studies, it has been difficult to ascertain a true causal relationship between soda […]
Silventoinen K, Jelenkovic A, Cozen W, Mack T, Sumathipala A, Christensen K, Busjahn A, Duncan GE, Buchwald D, Goldberg JH, Hopper JL, Sung J, Turkheimer E, Kaprio J, et al. Background Genes and the environment contribute to variation in adult body mass index [BMI (in kg/m2)], but factors modifying these variance components are poorly understood. […]
Reimann M, Schilke O, Cook KS. Why do people distrust others in social exchange? To what degree, if at all, is distrust subject to genetic influences, and thus possibly heritable, and to what degree is it nurtured by families and immediate peers who encourage young people to be vigilant and suspicious of others? Answering these questions could provide fundamental clues […]
Gasperi M, Herbert M, Schur E, Buchwald D, Afari N. Objective We used quantitative genetic methods to evaluate whether sleep quality, pain, and depression symptoms share a common genetic diathesis, to estimate the genetic and environmental sources of covariance among these symptoms, and to test for possible causal relationships. Methods A community sample of 400 […]
Zadro JR, Shirley D, Pinheiro MB, Bauman A, Duncan GE, Ferreira PH. The aim of this study was to investigate whether neighborhood walkability moderates the association between low back pain (LBP) and physical activity (PA), using a co-twin design to control for genetics and shared environmental factors. A cross-sectional analysis was performed on 10,228 twins […]
Bogl LH, Jelenkovic A, Christensen K, Cozen W, Mack TM, Duncan GE, Buchwald D, Hopper JL, Silventoinen K, Kaprio J, et al. Background The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric […]
Strachan E, Duncan G, Horn E, Turkheimer E. Background Depression is a significant problem and it is vital to understand its underlying causes and related policy implications. Neighborhood characteristics are implicated in depression but the nature of this association is unclear. Unobserved or unmeasured factors may confound the relationship. This study addresses confounding in a […]
Godfrey KM, Herbert M, Strachan E, Mostoufi S, Crofford LJ, Buchwald D, Poeschla B, Succop A, Afari N. Objectives Hypothalamic-pituitary-adrenal (HPA) axis dysregulation is associated with chronic pain. Studying pain sensitivity and the HPA axis could elucidate the role of stress in chronic pain development, which might be influenced by familial factors, including genes. Methods […]
Beam CR, Dinescu D, Emery R, Turkheimer E. Marriage is associated with reductions in both perceived stress and depressive symptoms, two constructs found to be influenced by common genetic effects. A study of sibling twins was used to test whether marriage decreases the proportion of variance in depressive symptoms accounted for by genetic and environmental […]
Watson NF, Buchwald D, Delrow JJ, Altemeier WA, Vitiello MV, Pack AI, Bamshad M, Noonan C, Gharib S. Habitual short sleep duration is associated with adverse metabolic, cardiovascular, and inflammatory effects. Co-twin study methodologies account for familial (e.g., genetics and shared environmental) confounding, allowing assessment of subtle environmental effects, such as the effect of habitual […]
