What Twin Studies Tell Us About Brain Responses to Food Cues

Schur E, Carnell S. Purpose of Review Functional magnetic resonance imaging (fMRI) using visual food cues provides insight into brain regulation of appetite in humans. This review sought evidence for genetic determinants of these responses. Recent Findings Echoing behavioral studies of food cue responsiveness, twin study approaches detect significant inherited influences on brain response to […]

A twin study of differences in the response of plasma ghrelin to a milkshake preload in restrained eaters

Myhre R, Kratz M, Goldberg J, Polivy J, Melhorn S, Buchwald D, Cummings DE, Schur EA Genetic, physiological, and psychological factors can affect food intake, but twin studies can distinguish inherited from environmental contributors. We examined the influence of attempted cognitive control of eating (“restrained eating”) on levels of appetite-regulating hormones. Sixteen female, monozygotic twin pairs, […]

Acquired differences in brain responses among monozygotic twins discordant for restrained eating

Schur EA, Kleinhans NM, Goldberg J, Buchwald DS, Polivy J, Del Parigi A, Maravilla KR We studied whether self-reported intent to exert cognitive control over eating was associated with differences in brain response to food cues, independent of genetic background. Subjects were ten pairs of identical twins in which one twin was a restrained eater […]

An Interdisciplinary Study of Eating Behavior in Twins

PI: Ellen SchurProject Number: 1K23DK070826Project Dates: 6/15/2005–5/31/2010 This K23 award will allow Dr. Schur to become an independent investigator proficient in the design and conduct of interdisciplinary research on eating behavior and weight regulation. The training and research activities focus on complex environmental and genetic influences on eating habits and appetite regulation. The application proposes an […]