SIP2

Genetic and environmental influences on posttraumatic stress disorder symptoms and disinhibited eating behaviors

Posttraumatic stress disorder (PTSD) and eating disorders (ED) frequently co-occur, but the mechanisms underlying this association remain unclear. EDs are characterized by features of maladaptive eating behaviors including disinhibited eating and cognitive dietary restraint. Identifying the genetic overlap between PTSD symptoms and maladaptive eating behaviors may elucidate biological mechanisms and potential treatment targets. A community […]

Genetic and Environment Influences on Sleep, Pain, and Depression Symptoms in a Community Sample of Twins

Objective: We used quantitative genetic methods to evaluate whether sleep quality, pain, and depression symptoms share a common genetic diathesis, to estimate the genetic and environmental sources of covariance among these symptoms, and to test for possible causal relationships. Methods: A community sample of 400 twins from the University of Washington Twin Registry completed standardized self-report questionnaires. […]

Heritability of Pain Catastrophizing and Associations with Experimental Pain Outcomes: A Twin Study

This study used a twin paradigm to examine genetic and environmental contributions to pain catastrophizing and the observed association between pain catastrophizing and cold-pressor task (CPT) outcomes. Male and female monozygotic (n = 206) and dizygotic twins (n = 194) from the University of Washington Twin Registry completed a measure of pain catastrophizing and performed […]