Watson NF, Buchwald D, Delrow JJ, Altemeier WA, Vitiello MV, Pack AI, Bamshad M, Noonan C, Gharib S. Habitual short sleep duration is associated with adverse metabolic, cardiovascular, and inflammatory effects. Co-twin study methodologies account for familial (e.g., genetics and shared environmental) confounding, allowing assessment of subtle environmental effects, such as the effect of habitual […]
Watson NF, Harden KP, Buchwald D, Vitiello MV, Pack AI, Strachan E, Goldberg J We used quantitative genetic models to assess whether sleep duration modifies genetic and environmental influences on depressive symptoms. Participants were 1,788 adult twins from 894 same-sex twin pairs (192 male and 412 female monozygotic [MZ] pairs, and 81 male and 209 female […]
Watson NF, Harden KP, Buchwald D, Vitiello MV, Pack AI, Weigle DS, Goldberg J To examine whether sleep duration modifies genetic and environmental influences on body mass index (BMI), investigators conducted a genotype-environment interaction twin study. the dataset included twin pairs from the University of Washington Twin Registry (1,088 pairs, 604 monozygotic, 484 dizygotic; 66% female; […]
Watson NF, Buchwald D, Noonan C, Vitiello MV, Pack AI, Goldberg J We used the community-based University of Washington Twin Registry to investigate the genetic association between circadian type and sleep duration. Habitual sleep duration was obtained by self-report and circadian type was measured using a reduced 5-item Horne–Östberg Morningness–Eveningness questionnaire. Univariate and bivariate genetic […]
