Zadro JR, Shirley D, Pinheiro MB, Bauman A, Duncan GE, Ferreira PH. The aim of this study was to investigate whether neighborhood walkability moderates the association between low back pain (LBP) and physical activity (PA), using a co-twin design to control for genetics and shared environmental factors. A cross-sectional analysis was performed on 10,228 twins […]
Bogl LH, Jelenkovic A, Christensen K, Cozen W, Mack TM, Duncan GE, Buchwald D, Hopper JL, Silventoinen K, Kaprio J, et al. Background The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric […]
Strachan E, Duncan G, Horn E, Turkheimer E. Background Depression is a significant problem and it is vital to understand its underlying causes and related policy implications. Neighborhood characteristics are implicated in depression but the nature of this association is unclear. Unobserved or unmeasured factors may confound the relationship. This study addresses confounding in a […]
Godfrey KM, Herbert M, Strachan E, Mostoufi S, Crofford LJ, Buchwald D, Poeschla B, Succop A, Afari N. Objectives Hypothalamic-pituitary-adrenal (HPA) axis dysregulation is associated with chronic pain. Studying pain sensitivity and the HPA axis could elucidate the role of stress in chronic pain development, which might be influenced by familial factors, including genes. Methods […]
Beam CR, Dinescu D, Emery R, Turkheimer E. Marriage is associated with reductions in both perceived stress and depressive symptoms, two constructs found to be influenced by common genetic effects. A study of sibling twins was used to test whether marriage decreases the proportion of variance in depressive symptoms accounted for by genetic and environmental […]
Watson NF, Buchwald D, Delrow JJ, Altemeier WA, Vitiello MV, Pack AI, Bamshad M, Noonan C, Gharib S. Habitual short sleep duration is associated with adverse metabolic, cardiovascular, and inflammatory effects. Co-twin study methodologies account for familial (e.g., genetics and shared environmental) confounding, allowing assessment of subtle environmental effects, such as the effect of habitual […]
Jelenkovic A, Sumathipala A, Christensen K, Hopper JL, Cozen W, Mack TM, Sung J, Duncan GE, Buchwald D, Harris JR, Goldberg JH, Kaprio J, Silventoinen K, et al. Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis […]
Dinescu D, Turkheimer E, Beam CR, Horn EE, Duncan G, Emery RE. Married adults have consistently been found to drink less than their single or divorced counterparts. This correlation may not be causal, however, as people nonrandomly “select” into marriage and into alcohol use. The current study uses a sample of 2,425 same-sex twin pairs […]
Sinclair VG, Wallston KA, Strachan E. Posttraumatic depression rates are increasing in the United States, and there is a great need to identify malleable factors that could moderate posttraumatic depression levels. The purpose of this study was to examine whether resilient coping moderates the effects of trauma exposure on depression, while controlling for neuroticism-an established […]
Silventoinen K, Jelenkovic A, Busjahn A, Cozen W, Mack TM, Craig JM, Harden KP, Duncan GE, Buchwald D, Goldberg JH, Kaprio J, et al. Background Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. Objectives We analyzed […]
