Harden KP

Education in Twins and Their Parents Across Birth Cohorts Over 100 years: An Individual-Level Pooled Analysis of 42-Twin Cohorts

Silventoinen K, Jelenkovic A, Hopper JL, Busjahn A, Cozen W, Mack TM, Sumathipala A, Harris JR, Goldberg JH, Harden KP, Duncan GE, Buchwald D, Turkheimer E, Kaprio J, et al. Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences […]

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

Silventoinen K, Jelenkovic A, Busjahn A, Cozen W, Mack TM, Craig JM, Harden KP, Duncan GE, Buchwald D, Goldberg JH, Kaprio J, et al. Background Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. Objectives We analyzed […]

Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

Jelenkovic A, Craig JM, Sumathipala A, Harden KP, Cozen W, Mack TM, Hopper JL, Duncan GE, Buchwald D, Sung J, Harris JR, Busjahn A, Goldberg JH, Kaprio J, Silventoinen K, et al. Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and […]

Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project

Jelenkovic A, Craig JM, Sumathipala A, Harden KP, Cozen W, Mack TM, Hopper JL, Duncan GE, Buchwald D, Sung J, Harris JR, Busjahn A, Goldberg JH, Kaprio J, Silventoinen K, et al. A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this difference […]

The CODATwins Project

The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits Silventoinen K, Craig JM, Sumathipala A, Harden KP, Cozen W, Mack TM, Hopper JL, Duncan GE, Buchwald D, Sung J, Harris JR, Busjahn A, Goldberg JH, Kaprio J, et al. […]

Sleep duration and depressive symptoms: a gene-environment interaction

Watson NF, Harden KP, Buchwald D, Vitiello MV, Pack AI, Strachan E, Goldberg J We used quantitative genetic models to assess whether sleep duration modifies genetic and environmental influences on depressive symptoms. Participants were 1,788 adult twins from 894 same-sex twin pairs (192 male and 412 female monozygotic [MZ] pairs, and 81 male and 209 female […]

A Twin Study of Genetic Influences on Diurnal Preference and Risk for Alcohol Use Outcomes

Watson NF, Buchwald D, Harden KP The population-based University of Washington Twin Registry (UWTR) was used to examine (1) genetic influences on chronobiology and (2) whether these genetic factors influence alcohol-use phenotypes. We used a reduced Horne-Östberg Morningness-Eveningness Questionnaire (rMEQ) to survey UWTR participants for diurnal preference. Frequency and quantity of alcohol use, as well as […]

Sleep duration and body mass index in twins: a gene-environment interaction

Watson NF, Harden KP, Buchwald D, Vitiello MV, Pack AI, Weigle DS, Goldberg J To examine whether sleep duration modifies genetic and environmental influences on body mass index (BMI), investigators conducted a genotype-environment interaction twin study. the dataset included twin pairs from the University of Washington Twin Registry (1,088 pairs, 604 monozygotic, 484 dizygotic; 66% female; […]