Publications

A twin study of posttraumatic stress disorder symptoms and chronic widespread pain

Previous studies of the association between posttraumatic stress disorder (PTSD) and chronic widespread pain (CWP) or fibromyalgia have not examined the role of familial or genetic factors. The goals of this study were to determine if symptoms of PTSD are related to CWP in a genetically informative community-based sample of twin pairs, and if so, […]

Is the association between posttraumatic stress disorder symptoms and poor health due to a common familial or genetic factor?

Objective: The objective of this study was to identify genetic, familial and environmental contributions to the association between posttraumatic stress disorder (PTSD) symptoms and poor health. Methods: A community sample of 1852 twin pairs was assessed for symptoms of PTSD [with the Impact of Events Scale (IES)] and self-reported global health status using a single five-level question. […]

Genetic and environmental influences on insomnia, daytime sleepiness, and obesity in twins

Study objectives: To better understand the relationships of insomnia, sleepiness, and obesity. Design: Classic twin study. Setting: A community-based twin registry in Washington State. Patients or participants: One thousand forty-two monozygotic and 828 dizygotic twin pairs participating in the University of Washington Twin Registry. Interventions: N/A. Measurements and results: Twins were, on average, 32 years old; 61% were women, and 19.5% […]

Genetic pleiotropy between asthma and obesity in a community-based sample of twins

Background: Asthma and obesity are common conditions that are strongly associated. This association might be due to shared genetic or environmental causes. Objective: We sought to determine whether a shared genetic cause is responsible for the association between asthma and obesity and to estimate the magnitude of shared genetic cause. Methods: The analyses were performed with 1001 monozygotic […]