Epidemiological studies typically rely on exposure assessments based on ambient PM2.5 concentrations at participants’ home addresses. However, these approaches neglect personal exposures indoors and across different non-residential microenvironments. To address this problem, our study combined low-cost sensors and GPS to conduct two-week personal PM2.5 monitoring in 168 adults recruited from the Washington State Twin Registry between 2018 and 2021. PM2.5 mass concentration, size-resolved particle number concentration, temperature, humidity, and GPS coordinates were recorded at 1-minute intervals, providing 5,161,737 datapoints. We used GPS coordinates and a processing algorithm for automatic classification of microenvironments, including seven land use types and vehicles, and time spent indoors/outdoors. The low-cost sensors were calibrated in-situ, using regulatory monitoring data within 600 m of participants’ outdoor measurements (R2 = 0.93). A linear mixed model was used to estimate the associations of multiple spatiotemporal factors with personal exposure concentrations. The average PM2.5 exposure concentration was 8.1 ± 15.8 μg/m3 for all participants. Indoor exposure concentration was higher than outdoor exposure level, and indoor exposure dose contributed 77% to the total exposure. Exposures in residential and industrial land use had a higher concentration than in other areas, and accounted for 69% of the total exposure dose. Furthermore, personal exposure concentration was the highest during winter and evening hours, possibly due to cooking and heating-related behaviors. This study demonstrates that personal monitoring can capture spatiotemporal variations in PM2.5 exposure more accurately than home-based approaches based on ambient air quality, and suggests opportunities for controlling exposures in certain microenvironments.
Liu N, Avery A, Austin E, Meschke JS, Beck NK, Carvlin G, Liu Y, Moudon AV, Novosselov I, Shirai JH, Duncan GE, Seto E. Using low-cost sensors and GPS to assess spatiotemporal variations in personal exposure to PM2.5 in the Washington State Twin Registry. Environ Res. 2025 Sep 23:122941. Epub ahead of print.