Secondhand Smoke and Asthma: Mechanistic Outcomes of DNA Methylation in T Cells
PI: Kari NadeauProject Number: 5R01HL118612Project Dates: 1/15/2014–12/31/2017 Exposure to secondhand smoke (SHS) is associated with a greater lifetime risk of developing asthma, more severe asthma, and increased asthma hospitalizations for both children and adults. While much of the immunopathogenesis of asthma remains incompletely understood, key molecular events include changes in regulatory T cell (Treg) and effector […]